Our environment has changed profoundly over the past 100 years. More than 90,000 new chemicals have been developed and integrated into our way of living without adequate testing to ensure safety for adults and, particularly, for children. As the number and quantities of chemicals in our environment has dramatically increased, so to have the patterns of disease changed among humans over the same post- World War II era, including a precipitous rise in incidence of type 2 diabetes, obesity, thyroid disease, asthma, allergy, autoimmune disease, autism, ADHD and several cancers.